Senior Scientist, Analytical Chemistry Job at Planet Group, South San Francisco, CA

ZHRvcmNZc21aZzl2bWhCQ2lCRkhsZ0RF
  • Planet Group
  • South San Francisco, CA

Job Description

Senior Scientist, Analytical Chemistry
The Position:

We are seeking an experienced, energetic, and enthusiastic individual to join the Analytical and Formulation Sciences group within the Drug Discovery department. This lab-based role is perfect for someone eager to deepen their expertise in analytical, formulation, and separation sciences along with physical chemical property measurement.  

In this role, you will play a crucial part in supporting the Drug Discovery group as we strive to bring new medicines to patients. As a key member of project teams, you’ll collaborate with experts in medicinal chemistry, DMPK, pharmacology, and biomarker departments. Together, you’ll help advance our programs from initial screening to clinical nomination. You’ll have the opportunity to work with top-of-the-line analytical instrumentation, including LCMSMS, Agilent HPLC 1260, Waters LCMS, PLM, Dissolution Apparatus, and a Rigaku Miniflex XRPD.  

Your Impact:
  • Independently develop chromatography methods with different modes such as normal phase, reverse phase, chiral and achiral for diverse compounds to support Drug Discovery projects.
  • Apply extensive hands-on experience to operate, maintain and troubleshoot mass spectrometers such as single-Q, Triple-Q, Q-TOF, Orbitrap, as well as SFC chromatography instruments.
  • Independently develop LCMS methods for characterizing advanced lead compounds, including but not limited to impurity profile, degradant identification, and structure elucidation of major impurities and degradants.
  • Conduct solid form measurements including thermodynamic solubility, particle size, polyforms, melting point, salt, and water content analysis.
  • Perform solid form measurements for advanced lead compounds; including solubility, particle size and polyform assessment, melting point, salt and water content of each lot.
  • Author analytical protocols and reports. Provide suggestions and troubleshoot potential issues in ongoing drug discovery projects. Coordinate and provide oversight during assay transfer between the company and external partner groups.
  • You will provide scientific mentorship and technical guidance for junior colleagues. 
Skills and Qualifications:
  • PhD with 7+ years or Master's with 10+ years of relevant experience in an academic, biotech, or pharmaceutical industry
  • Degree in Analytical Chemistry, Organic Chemistry, Biochemistry, Pharmaceutical Sciences, or related discipline
  • Extensive hands-on experience with HPLC, LCMS, LCMSMS, ELSD, or CAD, Karl Fisher, Ion Chromatography, DSC, and reverse phase/normal phase/chiral chromatography
  • Strong method development skills including experience with reverse phase, normal phase and SFC liquid chromatography, mass spectrometry, fragmentation mass spectrometry, ELSD/CAD, and SFC separations.
  • Experience in analytical assay development, quantitative analysis, impurity elucidation, high throughput QC, and library screening.
  • Excellent interpersonal and leadership skills for cross-functional collaboration.

Job Tags

Permanent employment,

Similar Jobs

Archer Travel

Work From Home Travel Agent Job at Archer Travel

REMOTE TRAVEL AGENT - WORK FROM ANYWHERE! LOCATION: REMOTE (MUST RESIDE IN THE UNITED STATES, UNITED KINGDOM, OR MEXICO) Do you have...  ...to join our team as Remote Travel Agents! No prior experience is necessary - we provide comprehensive training to set you up... 

VRK IT Vision Inc

Oracle Fusion Technical Consultant Job at VRK IT Vision Inc

 ...Hi, I hope you are doing well. Role: Sr. Oracle Fusion Technical Consultant - ITS Start Date: September 2025 Contract duration: 6 months. Location: Remote (Only Local profiles accepted) Job Description Seeking highly skilled Oracle... 

CRF Behavioral Healthcare

Nurse - RN Job at CRF Behavioral Healthcare

 ...Excellence in Behavioral Health Services in San Diego County! Hours : 16 hours per week; Saturday and Sunday, 8:00 am to 4:30 OR...  ...current during employment As a Nurse - RN , you will be part of a team that assesses clients mental and physical health and... 

Monty's Express Carwash

Car Wash Attendant (Sacramento) Job at Monty's Express Carwash

 ...local, family-owned business? Enjoy working with customers? Enjoy learning and growing? Our Benefits: Competitive Pay Including daily cash tips , monthly commissions, annual incentives. FREE car washes for your personal or family vehicle. Flexible... 

Charles Utilities Inc.

Directional Drill Operator/Foreman Job at Charles Utilities Inc.

 ...Directional Drilling) and trench (Machine trenching). Job Details: Job Type: Full-time. Pay: $22.00 - $27.00 per hour based on experience. Work Location: On the road. Requirements: Valid Drivers License Benefits include: Life, Death, Short and Long Term...